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Cycle: 
23 cycle
Tutor: 
Prof. Gianni Pedrizzetti
Advisor: 
Dr. Luigino Zovatto, Università di Trieste
Curriculum, Annual Report, Thesis: 
Current Position: 

Postdoc at Clemson University

Scientific Activity: 

Her research interests comprise the cardiovascular fluid mechanics, data extraction from medical imaging, development of novel medical devices and patient-specific modeling of cardiovascular diseases and treatments. Currently her study is focused on the fluid-structure interaction that occurs when a movable leaflet faces an otherwise free stream. The analysis is performed in theoretical terms, by means of the solution of the two-dimensional Navier-Stokes equation using body-fitted moving coordinates. The aim is to reproduce and improve the understanding of vortex formation from an obstacle moved by the unsteady, pulsed, flow itself. The study is stimulated by the need of constructing physically-based interpretative schemes for the motion of the leaflets of cardiac valves. The work contains also the experimental comparison of the performance of standard mechanical heart valves and those of homemade asymmetric prototypes, mounted inside the artificial model of the heart. The study includes the PIV analysis of the vortical flow patterns inside the left ventricle in the presence of artificial implants.

Background: 

Marija earned both B.S. and M.S. degree in Chemical engineering from University of Belgrade, Serbia. Her master thesis was on "Characterization and Process Development of Supercritical Fluid Extraction of Sage oil", September 2007. Marija received her PhD from the University of Trieste in Italy in May 2011. Her doctoral research has been guided by Prof. Gianni Pedrizzetti and focused on "Vortex formation behind a movable leaflt - Numerical and Experimental study".

Publications: 
  • Pedrizzetti G. and Vukicevic M., Vortex formation and growth behind an orifice, Conference XIX Congress AIMETA, Ancona, September 2009.
  • Vukicevic M, Pedrizzetti G. Role of inertia in the interaction between oscillatory flow and a wall-mounted leaflet. Phys Rev E 2011; 83(1):016310.
  • Vukicevic M, Pedrizzetti G. On the opening of a wall-mounted leaflet by a single flow pulse. Phys Rev E 2011; 84:017301.
  • Vukicevic M, Fortini S, Querzoli G, Cenedese A, Pedrizzetti G. Experimental study of asymmetric mechanical heart valve prototype, EJMB 2012, Special Issue.
  • Vukicevic M, Chiulli J.A, Conover T, Pennati G, Hsia T.Y, Figliola R.S, MOCHA NetworkMock. Circulatory System of the Fontan Circulation to Study Respiration Effects on Venous Flow Behavior, ASAIO Journal May-June 2013 issue.
Conferences: 
  • EUROMECH 529 Cardiavascular Fluid Mechanics, June 2011, Cagliari, Italy.
  • 64th Annual Meeting of the APS Division of Fluid Dynamics, November 2011, Baltimore, MD. Highlited presentation of the day: http://www.breakthroughdigest.com/medical-news/new-design-for-mechanical...
  • ASME 2012 Summer Bioingeneering conference, Puerto Rico.
  • International Conference on Engineering Frontiers in Congenital Heart Diseases, Stanford University 2012.
  • 65th Annual Meeting of the APS Division of Fluid Dynamics, November 2011, San Diego, CA